FacebookTwitterLinkedInEmailPrint分享Energy Magazine:Final testing has begun on South Australia’s 150MW Hornsdale Power Reserve, the biggest lithium-ion battery in the world, which is owned by Neoen.The South Australian Government provided $15 million from its Grid Scale Storage Fund for the project.South Australian Minister for Energy and Mining, Dan van Holst Pellekaan, said the start of testing is a key milestone for the Hornsdale Power Reserve, which will allow the huge battery to provide new grid support services at a scale unmatched in the world.Mr van Holst Pellekaan said that the additional storage power and capacity would result in a faster response to disturbances such as network faults, so that the Hornsdale Power Reserve could assist in stabilising the grid within milliseconds.“Independent modelling indicates that the Hornsdale Power Reserve has already delivered more than $150 million in savings to consumers in its first two years of operation. Upon successful completion of testing in the next few months, we expect these savings will continue to grow.”[Imogen Hartman]More: SA’s big battery hits final testing phase Final testing under way at expanded Hornsdale Power Reserve in South Australia
THE Flying Stars Cycle Club (FSCC) will stage a 25-lap cycle road race around the outer circuit of the National Park on Sunday, in memory of five of its past executives who have all passed away.According to the club’s treasurer William Howard, the event is in memory of the FSCC’s former executives Charles Chichester, Donald Robinson, Oswald Taitt, Cecil Anderson and Stanley Boyce.The event will cater for five category of cyclists and will commence at 09:00hrs from outside the National Park entrance on Carifesta Avenue.The categories that will be involved are Open/seniors, Juniors, Veterans Under-45 years of age and Over-45 years as well as Mountain bikers.Howard disclosed that the activity is being sponsored by former national cyclists in the Diaspora including former national champions Neville Hunte, Victor Rutherford, Monty Davis, Randolph Toussaint and M. Rogers.Chichester once served as the club’s vice-president and was also a vice-president of the Guyana Cycling Federation (GCF). He was also the Sunday Editor of the Guyana Graphic (now Guyana Chronicle).Robinson who acted as president of the Guyana Olympic Association for a short time was the club’s president and also served as second vice-president of the GCF.Taitt was once a vice-president of the club and was racing secretary of the GCF as was Anderson who served in both capacities. Boyce, on the other hand, was an ordinary club member.
*Circle of Friends will have Movie Day onÂ Thursday Nov. 13Â during 6th, 7th and 8th hours. Â COF members will report to 6th hour and be dismissed by intercom. Todayâ€™s News Thursdayâ€™s lunch: Thanksgiving dinner: chicken and dressing, potatoes/gravy, green beans, hot roll/jelly, pumpkin dessert.Â *Crusader Creators will NOT have a meeting today. *Reminder to Athletes:Â November 10 – 16Â is Fall Buffer Week. No activities in any school gyms during this week. Submitted to Sumner Newscow â€” Todayâ€™s Wellington High School bulletin for Wednesday, November 12, 2014:WednesdayThursdayâ€¢ Scholarsâ€™ Bowl at Bishop CarrollFriday – Nothing!Wednesdayâ€™s lunch: Fajita wrap, romaine and tomato, spanish rice, steamed carrots, peaches. *STUDENTS: If you are participating in a winter sport and do not have a physical or concussion form on file, you must do so before you will be allowed to practice. You can pick up the forms in the counselor’s office. *Seniors: Please start turning in your needed pictures for the graduation video, along with your top 3 song choices to be in the video. You can turn them into Mrs. Vaughn in room 203, Leah Nelson or Shayna Templeton. Please turn them in ASAP. *There is a sign-up sheet in the office for Special K Basketball. Please sign up by November 25th. *Classic Movie club will be showing the movie â€œThe King and Iâ€ at 3:30 on Thursday, November 13 in room 205. Bring a friend! *Upward Bound will be hereÂ today during lunch if you’d like to speak with them about signing up for a great program!Guidance Office News:College visits during lunch:Thursday, November 13- Fort Hays CollegeTuesday, Nov. 18Â – Hesston College
By Jenna O’Donnell | OCEANPORT – Every August the community gathers for a big race at Monmouth Park Racetrack, but it’s not the Haskell Invitational that draws this crowd.The Kortney’s Challenge 2-Mile Fun Walk Run is sneakers on pavement instead of hooves on dirt, and it’s all about raising money to fund pediatric brain cancer research. Now gearing up for the 13th annual Kortney’s Challenge event, The Kortney Rose Foundation (KRF) has continued to grow over the years, bringing awareness and needed funding to a cause inspired by 9-year-old Kortney Rose Gillette, who died in 2006 after she was diagnosed with an inoperable brain tumor.Kortney’s mother, Kristen Gillette, started what would become the Kortney Rose Foundation in the months following her daughter’s death and to date the organization has raised nearly $2 million dollars to fund research into pediatric brain tumors. Gillette, along with her husband Rich and daughter Kasey, credits much of the nonprofit’s success to the love and support of their community.“The support of our small town has enabled us to help turn a negative into a positive,” Gillette said. “KRF is making a large impact in supporting research for kids with brain cancer. It’s all from the grassroots efforts begun in Oceanport.”The Gillette’s foundation was one of the initial supporters behind a collaborative research program dedicated to the study of childhood brain tumors known as Children’s Brain Tumor Tissue Consortium (CBTTC). The consortium’s open-access, data driven approach has enabled top researchers from around the world to develop diagnostic tests and treatments more quickly. As a thank-you to the Gillettes for their support, the CBTTC dedicated its initial research project to the type of brain tumor that Kortney was diagnosed with. It is the largest research project that has ever been done for that type of cancer.“That meant a lot,” Gillette said. “We’ve been supporting research for all other kinds of tumors in the hopes that someday there would be something really good that we can invest in.”In an effort to further support the CBTTC, Gillette has joined up with three like-minded nonprofits across the country in a collaboration known as 4 Pennies – which speaks to the 4 cents of every dollar that the National Institute of Health donates to fund pediatric cancer research.“Ninety six percent of funding goes to adults and 4 percent to all pediatric cancer research,” she said. “Our small foundation funds that research because the government doesn’t.”While KRF looks toward supporting pediatric brain tumor researchers across the country, the local grassroots effort to raise money and awareness at home continues, and often inspires others to step up and get involved.Charlotte Kaye, as a sophomore at Ranney School, heard about the Gillette’s story when her dancing school in Little Silver got involved in fundraising. Kaye, who had survived a childhood brain tumor, said she had always wanted to find a way to get involved and give something back. She and her friends started a three-hour danceathon at their school that year. By the time Kaye graduated three years later, she had helped to raise $22,000 toward pediatric brain tumor research.Monmouth Park, an early sponsor and host to KRF events, continues to proudly support the fundraising efforts, said Brian Skirka, the track’s marketing director.“To be able to support a local organization like the Kortney Rose Foundation from the early stages to now is something special – to see how the event has grown and how much money is raised for pediatric brain cancer research,” he said. “So much of Kortney’s Challenge is based on community support and Monmouth Park is happy to be a part of that.”The borough community, staff, local groups and elected officials have also been involved with the KRF since the beginning, hosting dinners, supporting fundraising efforts in local schools and turning up to new events, such as the Pony Up for Kids family event in May.Oceanport Mayor Jay Coffey, who met the Gillettes in 2005 when their children played soccer together, remembers Kortney as a fun-loving girl filled with energy and enthusiasm.“Our town is lucky to have people like the Gillettes,” he said. “They’ve made something positive out of an incredibly tragic situation. The whole town has really rallied behind Kortney’s Challenge. It’s a wonderful thing to remember a beautiful little girl. I can’t think of a more worthy cause.”The 13th annual Kortney’s Challenge Fun Walk Run at Monmouth Park will take place 8:30 a.m. Sunday, Aug. 5. Online registration for the event is currently available at the foundation’s website thekortneyrosefoundation.org.Gillette and her family are hopeful for another successful year, as they continue to fund research to help doctors to help kids.“We are beyond grateful to our community who has helped us to donate over $1.7 million dollars to research,” Gillette said.This article first appeared in the July 12 – 19, 2018 print edition of The Two River Times.
“We’re up over 300 registrations,” said Kim Irving, in charge of registration for the Cyswog’n’Fun.”This being our 30th anniversary we wanted to have a good turnout so we offered a $30 (early bird) fee, which seemed to help.”The action begins with the starter’s pistol at 8 a.m from the beach at Lakeside Park.Competitors take to the water for the 1500 meters swim — short course, 500 meters — before switching gears to the bike for the 39 km trek on along beautiful Kootenay Lake to Kokanee Park and back.Short course participants turn at Lower 6 Mile Road.After the cycle, it’s running shoes time as competitors trek along the waterfront, around Anderson Street and then Nelson Avenue and across the orange bridge onto the rolling hills of Johnstone Road.Sprint course turns around on Valhalla Rd, returns via the bridge and turns right on Kokanee Avenue and right again on Second Street into the park.Spectators are welcome. Did you know that in 1982 the Commodore 64 computer and the first CD player by Sony were released.The shift in technology was so significant that Time Magazine named The Computer as the person of year in 1982.Another major event taking place happened in Nelson when Jennifer Stanger and Sandy and Danny Babin parlayed an idea during a trip south of the border into the Cyswog’n’Fun Triathlon.Sunday, organizers, competitors and volunteers will blow out the candles on 30 years of swimming, cycling and running at Lakeside Park.
Like soldiers in a foreign land, cells sometimes find themselves in unexpected situations. Key equipment breaks down, or the environment puts stress on their resources. Without the ability to adapt, they could perish – and in worst-case scenarios they must, like a squadron under ambush with no way out. In such cases, like spies carrying cyanide vials, cells commit orderly suicide for the good of the organism. Two papers in Science describe how cells do it. DNA damage is like an emergency in the field. Fortunately, cells have elaborate procedures for dealing with it, like a flowchart, where remaining resources adapt and fix the damage. Israeli scientists Friedman and Schuldiner,1 summarizing a paper in the same issue of Science,2 described the “DNA Damage Road Map.” Bandyopadhyay et al had “discovered widespread changes in genetic interaction among yeast kinases, phosphatases, and transcription factors as the cell responds to DNA damage.” The technique they used was like turning still pictures into a movie: “Differential interactions uncover many gene functions that go undetected in static conditions.” Notably, “The data also reveal that protein complexes are generally stable in response to perturbation, but the functional relations between these complexes are substantially reorganized.” Friedman and Schuldiner described how the team had put yeast cells under stress by adding methyl methanesulfonate, a DNA-damaging agent, and watched how they behaved differently from those in a stable environment. The genetic networks reorganized themselves to handle the situation; “A bird’s-eye view of the dE-MAP reveals that protein complexes tended to remain stable across the two conditions,” they said. “The relationships between these complexes, however, were reprogrammed to assist the cell in dealing with stress.” For instance, a transcription factor affected “cell cycle checkpoints (which ensure the fidelity of cell division).” Being able to see networks respond in sequence represents a new frontier in biochemistry, they said. What’s more, “There are hundreds of such stories in the data.” Sometimes, when the stress is too great, death is the only option. Every day in your body, millions of cells die due to stress, injury, infection, or “the natural cell turnover process that is essential to optimal tissue functioning. That’s what Seamus J. Martin said in another Perspective piece in Science,3 describing how Ren et al, in the same issue,4 helped to resolve how cells execute the orderly process of cell suicide, called apoptosis. “A cell must commit suicide at the appropriate time, otherwise malfunctioning or damaged cells could accumulate and lead to tumor development and other pathological conditions,” Martin said. “Thus, sensors are needed to monitor the integrity of cellular functions and relay this information to the cell death machinery.” What Ren et al found is a “battery of sensors” that “detect cellular stress or damage through transcriptional or posttranslational mechanisms,” Martin said. He described what happens when the suicide alarm sounds: Upon activation, Bh3-only proteins provoke permeabilization of the mitochondrial outer membrane, allowing release of cytochrome c to the cytosol. This efflux triggers assembly of the apoptosome, a structure that sets in motion a proteolytic cascade that coordinates cell death through destruction of hundreds of proteins (see the figure). Because of their ability to unlock this cellular poison cabinet, Bh3-only proteins have come under intensive scrutiny. How do these proteins provoke cytochrome c efflux? Bax and Bak, proteins that either reside in or insert into mitochondrial membranes, constitute the pore or channel that permeabilizes mitochondria. Loss of Bax and Bak renders cells resistant to permeabilization (and subsequent apoptosis) caused by Bh3-only proteins. Upon activation, Bh3-only proteins promote oligomerization of Bax and Bak within the mitochondrial outer membrane. Thus, opening of the resultant channel effectively constitutes the decision to commit cellular suicide.In other words, the sensors open the gates to prisoners who call the cellular council to assemble a death machine, which holds the keys to a poison cabinet. During the process, a debate between pro-survival agents and death agents act like guards at the mitochondrial membrane checking one another’s credentials. “Thus, Bh3-only proteins and prosurvival Bcl-2 proteins represent opposing forces in the struggle to control the channel, the outcome of which dictates whether a cell will live or die.” A checking of codes in a nuclear weapons activation process comes to mind. “Because of the deadly consequences of mitochondrial outer membrane permeabilization, this major checkpoint on the road to cell death is heavily policed,” Martin said. When death is the only option remaining, it occurs in an orderly, systematic manner that leaves the rest of the organism at less risk. For more on apoptosis (programmed cell death), see 04/09/2002, 06/27/2003, 01/05/2006, 07/25/2006, 03/17/2007 and 08/14/2007.1. Nir Friedman and Maya Schuldiner, “Genetics: The DNA Damage Road Map,” Science, 3 December 2010: Vol. 330 no. 6009 pp. 1327-1328, DOI: 10.1126/science.1199862.2. Bandyopadhyay et al, “Rewiring of Genetic Networks in Response to DNA Damage,” Science, 3 December 2010: Vol. 330 no. 6009 pp. 1385-1389, DOI: 10.1126/science.1195618.3. Seamus J. Martin, “Cell Biology: Opening the Cellular Poison Cabinet,” Science, 3 December 2010: Vol. 330 no. 6009 pp. 1330-1331, DOI: 10.1126/science.1199461.4. Ren et al, “BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program,” Science, 3 December 2010: Vol. 330 no. 6009 pp. 1390-1393, DOI: 10.1126/science.1190217.Did you have any idea of the drama occurring inside your body millions of times a day? Your cells are constantly struggling against real foes: genetic mistakes, toxins, environmental stress, injury, infection, and overcrowding. Fortunately, there are elaborate policies and procedures, with police and programs, knowing how to handle each situation. None of these papers said anything about evolution. No wonder; this all sounds so much like intelligent design, it brings to mind images of cellular governments with documented foreign policy and homeland security systems. And the first paper was talking about yeast cells! How on earth can anyone continue holding on to a doctrine like Darwinism that was concocted by a guru (02/15/2004 commentary) who knew nothing of what was happening in the little globs of protoplasm mischaracterized by the scientists of his day? Martin talked about information being conveyed by these cellular agents, leading to decisions. The other papers talked about whole networks of information adapting to change by adjusting their interactions – including assessing the extent of damage, accelerating or repressing gene translation, and striving to maintain stability in response to stress. Only two things on earth we know of do that kind of thing: human minds, and robotic systems programmed by human minds. But human minds did not program the cell. What does that imply? Think, now, those of you who consider yourselves heirs of the Age of Reason.(Visited 23 times, 1 visits today)FacebookTwitterPinterestSave分享0
Founder: Lonely Road FoundationWhy is Thabang a Trailblazer?When this 31-year-old set up the Lonely Road Foundation to help rural communities support their orphans and vulnerable children, he knew he had to find an innovative way to raise awareness and funds for the cause.What he came up with was truly inspirational – a 5 500 kilometre solo bicycle ride from Johannesburg to Mount Kilimanjaro that would end in his summiting Africa’s highest peak.For Thabang, it was very important that his Lonely Road Challenge drew a direct parallel to the lives of children who grow up alone and unsupported throughout their childhoods and then, once they pass this milestone, are expected to become a productive member of society.This final task is what Thabang saw as the “mountain” they had to climb at the end of their “Lonely Road”.In his own words…“If one person is inspired to make a difference, if one child is helped, then that is also something that I can take to my grave and say that at least I have made a difference in at least one person’s life.”Fast FactsThabang left a successful career in merchant banking to start an HIV/Aids and Wellness company called Kaelo.The Lonely Road Challenge took three months to complete and covered six countries.Thabang followed a strict schedule, riding for six days and resting for one.The challenge raised R676 000 raised for the Lonely Road Foundation.Thabang survived many hardships, including a mugging, being hit by a truck and weight loss of 14 kilograms.Thabang’s next challenge is to ensure that every cent of the Lonely Road Challenge goes to help projects supporting orphans and vulnerable children across South Africa.How can I help?You can support Thabang and his team by donating online at the Lonely Road FoundationContact the Lonely Road FoundationTel: 011 778 4340Fax: 011 778 4344Story published on SAinfo on 25 April 2008.Source: Brand South Africa
Each square represents a cluster of geocachesA milestone 14-years in the making reached yesterday at 7:45 am as the millionth geocache was published in the U.S.1,000,000 reasons for Americans to get off the couch and explore their neighborhoods are waiting to be discovered and some are likely within walking distance. Geocaching.com launched in 2000, listing just 75 hidden geocaches. As of 7:45 am EST on Sunday, September 14, the 1,000,000th active geocache in the U.S. was published on Geocaching.com. The 1,000,000th active geocache is called Daddy’s Fishing Hole, located near Chambersburg, Pennsylvania.As of 9:00 am PCT on Monday, September 15, the 1,000,000th geocache has only been found only three times. To celebrate the 1,000,000th active geocache in the United States, the staff at Geocaching.com named the top 8 most amazing geocaches for beginners in the U.S.The 8 Most Amazing Geocaches for Beginners in the U.S. Geocaching is increasingly popular with families Geocachers occasionally arrange their geocache hides in the form of county-sized art. There are currently 2,487,221 active geocaches hidden around the world – in 2013 alone geocachers were found 75,453,001 times. Follow the yellow brick road to this geocache in Saratoga, Springs, NY. Texas A&M just published an independent, CDC-funded study on the health benefits of geocaching. Geocaches can be found in all 50 US states SharePrint RelatedThe Two Millionth Active Geocache – Overwatch #1 (GC46N4E) – Geocache of the WeekMarch 6, 2013In “Community”Celebrate the evolution of geocaching with the Big Blue Switch souvenir!April 25, 2017In “Community”Stone Park Jamshidieh GC2QDY1 GEOCACHE OF THE WEEK – April 30, 2012April 30, 2012In “Community” Share with your Friends:More Geocachers in Hershey, PA will be able to channel their inner Indiana Jones with this adventure. One AA battery is all new geocachers in Seattle, WA need to unlock this geocache. Just outside Milwaukee, WI, adventure-seekers will have a little extra help from some geocaching chickens. Geocaching events will be held near each of the sites the weekend of the September 20 to cheer on the 1,000,000th geocache and welcome new geocachers to the adventure. Expert geocachers will attend each of the geocaching events to guide new people through the free adventure. They’ll also give insider tips and tricks, and help find the geocache. New geocachers should register for the events and anyone can find a geocache near them now.There are more than 6,000 hidden geocaches in Alaska aloneMore than 2,000 hidden geocaches are waiting to be found across Hawaii Germany is second to the U.S. in active geocaches with 325,000. California holds the record for the state with the most active geocaches, boasting more than 130,000 hidden geocaches. The oldest active geocache in the U.S.. published in May of 2000, is located in Mingo, Kansas. Nearly 11 million people have registered for accounts on Geocaching.com since 2000. Visitors to Blackshear, GA can discover a newspaper box that’s out of the ordinary. Visitors to Fremont, CA, will learn the best way to catch a geocacher (and it might just involve a giant mouse trap). Geocache containers can look like almost anything… they should never be buried and should always be clearly labeled.Most people in the U.S. walk or drive by dozens of hidden geocaches nearly every day Congratulate the 1,000,000th geocache owners in comments below! Unlock a 1890’s history lesson involving Moon Towers in Austin, TX. Stop by Denver, CO to find a geocache that’s a puzzle and a fashion statement.
About the authorCarlos VolcanoShare the loveHave your say Juventus goalkeeper Szczesny: Dybala made difference for Lokomotiv Moscow winby Carlos Volcano3 days agoSend to a friendShare the loveJuventus goalkeeper Wojciech Szczesny was always confident of victory over Lokomotiv Moscow.The Russians had taken a shock lead after 30 minutes, but Dybala scored twice in two minutes late in the second-half to win this Champions League clash 2-1.“It was a struggle to get the result, but we controlled the game for 90 minutes and needed a lot of patience to break them down, as they were very organised and put a solid wall back there,” the goalkeeper told Sky Sport Italia.“A great left-foot shot from Dybala made the difference. Lokomotiv were clammed up in defence and we had to move the ball from left to right and back again to open up some spaces.“We must continue being protagonists in Serie A too and that means getting three points against Lecce this weekend.”
TagsTransfersAbout the authorCarlos VolcanoShare the loveHave your say Mijatovic can see Mourinho returning to Real Madridby Carlos Volcano2 days agoSend to a friendShare the loveFormer Real Madrid sports chief Predrag Mijatovic can see Jose Mourinho returning to the club.Mourinho is being linked with Zinedine Zidane’s job at Real.And Mijatovic admits he can see it happening: “If Zidane came back and I never thought it would happen, why can’t Mourinho return to Real Madrid? “All the coaches who go through Madrid want to come back because they want to fix things they did during their time at the club.”But Madrid has a coach, his name is Zidane and you have to respect that.”